Boneheel 0.5 mcg Tablets (Alfacalcidol)

Boneheel 0.5 mcg Tablets (Alfacalcidol)

Generic Name: Alfacalcidol (Vitamin D analogue)
Strength: 0.5 mcg per tablet
Pack Size: 3 × 10’s
Trade Price (T.P): PKR 595/-
Maximum Retail Price (M.R.P): PKR 700/-

Description:

Boneheel 0.5 mcg Tablets contain Alfacalcidol (1α-hydroxycholecalciferol), a synthetic vitamin D analogue used to manage hypocalcemia, secondary hyperparathyroidism, osteodystrophy, and bone mineralization disorders associated with chronic kidney disease, rickets, osteomalacia, and osteoporosis ([turn0search1]turn0search12]).

Key Features:

• Enhances intestinal calcium and phosphate absorption, promotes bone mineralization

• Bypasses kidney activation—effective even in renal impairment

• Helps reduce parathyroid hormone (PTH) levels in hypocalcemia

• Well-established efficacy in managing bone and mineral disorders

• More predictable effects compared to native vitamin D3 ([turn0search1]turn0search4])

Dosage & Administration:

• Adults and adolescents (>20 kg): 0.5 mcg once daily, ideally after breakfast

• Elderly patients: Often maintained at 0.5 mcg daily; some may require up to 1 mcg/day based on biochemical response ([turn0search4]turn0search11])

• Dose adjustments may be required based on serum calcium, phosphate, and PTH levels, typically monitored every 1–4 weeks initially

Precautions:

• Contraindicated in hypercalcemia or history of vitamin D toxicity

• Caution in renal impairment, cardiac disease, or disorders of calcium metabolism

• May cause headache, nausea, hypercalciuria, hypercalcemia, or muscle weakness

• Avoid co-administration with thiazide diuretics or digitalis due to risk of calcium-related arrhythmias ([turn0search4]turn0search5])

• Requires periodic monitoring of serum electrolytes and renal function

Storage:

• Store below 25 °C in a dry, cool place

• Protect from light and moisture

• Keep out of reach of children

Disclaimer:

This is a prescription-only medication. Use only under the guidance of a licensed healthcare professional. The information provided is for reference and does not replace medical advice. Always follow your doctor’s instructions.