Dezatax 500 mg Injection (Cefotaxime)

Dezatax 500 mg Injection (Cefotaxime)

Generic Name: Cefotaxime
Strength: 500 mg
Pack Size: 1’s
Trade Price (T.P): PKR _________
Maximum Retail Price (M.R.P): PKR __________

Description:

Dezatax 500 mg Injection contains Cefotaxime, a third-generation cephalosporin antibiotic effective against both Gram-positive and Gram-negative bacteria. It is indicated for treatment and prophylaxis in severe infections such as pneumonia, urinary tract infections, septicemia, skin and soft tissue infections, meningitis, and intra-abdominal infections. Cefotaxime inhibits bacterial cell wall synthesis, resulting in rapid bactericidal activity.

Key Features:

• Broad-spectrum bactericidal action against pathogens including E. coli, Streptococcus spp., Haemophilus influenzae, and Neisseria gonorrhoeae

• Elevated dosing for serious infections ensures therapeutic plasma levels

• Administered via IV or IM in hospital and ambulatory care settings

• Third-generation cephalosporin with enhanced β-lactamase resistance

• Packaged in single-dose vials for convenient on-demand reconstitution

Dosage & Administration:

• Adults (mild to moderate infections): 500 mg every 6–8 hours IV/IM

• Adults (severe infections, e.g., meningitis or sepsis): Up to 2 g every 6–8 hours, depending on clinical severity

• Pediatrics: 50–100 mg/kg per dose every 6–8 hours as prescribed

• Administer via slow IV injection (3–5 minutes) or infusion, or deep IM injection after reconstitution

• Adjust dosage in cases of renal impairment

Precautions:

• Contraindicated in patients with known hypersensitivity to cephalosporins or beta-lactams

• Monitor renal function; adjust dosage in renal insufficiency

• Rare risk of neurotoxicity (e.g., encephalopathy, seizures), especially in renally impaired or elderly patients

• Use cautiously during pregnancy and lactation—prescribe only if clinically justified

• Prolonged use may lead to superinfections, including Clostridioides difficile–associated diarrhea

Storage:

• Store between 15 °C and 25 °C in a dry, protected place

• Shield from moisture and direct sunlight

• Use reconstituted solution immediately or within the stability time specified by the manufacturer

• Keep out of reach of children

Disclaimer:

This product profile is intended for professional reference only and should not substitute clinical judgment. Administer under the supervision of a qualified healthcare provider. Pricing and availability may vary based on brand and supplier.