Lefonate 20mg Tablets (Leflunomide)
₨1,350.00
Lefonate 20mg Tablets (Leflunomide)
Generic Name: Leflunomide
Strength: 20mg
Pack Size: 3 × 10’s
Trade Price (T.P): PKR 1147.50
Maximum Retail Price (M.R.P): PKR 1350.00
Description:
Lefonate 20mg Tablets contain Leflunomide, an immunomodulatory and anti-inflammatory agent used primarily for the treatment of rheumatoid arthritis and psoriatic arthritis. It works by inhibiting pyrimidine synthesis, thus reducing the proliferation of activated lymphocytes that contribute to inflammation and joint damage.
Key Features:
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Disease-modifying agent for autoimmune joint disorders
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Reduces joint pain, swelling, and stiffness
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Slows disease progression and prevents joint damage
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Suitable for long-term use under medical supervision
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May be combined with methotrexate or other DMARDs
Dosage & Administration:
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Adults: 20mg once daily, with or without food
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Loading dose (optional): 100mg daily for first 3 days under physician guidance
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Swallow tablet whole with water; do not crush or chew
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Requires regular liver function monitoring during therapy
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Dosage adjustments may be required based on tolerability and lab results
Precautions:
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May cause elevated liver enzymes, diarrhea, headache, or rash
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Contraindicated in pregnancy due to risk of fetal harm
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Not recommended in patients with liver disease or immunodeficiency
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Monitor CBC, liver enzymes, and blood pressure regularly
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Requires cholestyramine washout before pregnancy or in case of toxicity
Storage:
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Store below 30°C in a dry place
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Protect from light and moisture
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Keep out of reach of children
Disclaimer:
Use this medication only under the guidance of a rheumatologist or qualified healthcare provider. The information provided is for educational purposes and does not substitute for professional medical advice. Always follow your doctor’s instructions precisely.
