Meprageen 40mg Capsules (Omeprazole)

Generic Name: Omeprazole
Strength: 40 mg
Pack Size: 2 × 7’s
Trade Price (T.P): PKR 365.50
Maximum Retail Price (M.R.P): PKR 430.00

Description:

Meprageen 40mg Capsules contain Omeprazole, a proton pump inhibitor (PPI) that effectively reduces gastric acid secretion by targeting the H⁺/K⁺ ATPase enzyme in the stomach lining. It is commonly prescribed for the treatment of severe acid-related conditions such as erosive esophagitis, peptic ulcers, GERD, and Zollinger-Ellison syndrome.

Key Features:

• High-dose acid suppression for severe or resistant cases.

• Promotes rapid healing of gastric and duodenal ulcers.

• Useful in GERD unresponsive to lower doses.

• Once-daily dosing with potential for twice-daily use in certain conditions.

• Effective in combination therapy for H. pylori eradication.

Dosage & Administration:

• Adults: 40 mg once daily before meals.

• For more severe conditions, dosage may be adjusted or split to 20 mg twice daily as directed.

• Usual treatment duration:

  • Erosive esophagitis: 4–8 weeks

  • Refractory GERD or ulcers: As per physician’s advice

• Swallow capsules whole; do not crush or chew.

• Follow physician’s guidance on dosage adjustments.

Precautions:

• Contraindicated in patients with known hypersensitivity to Omeprazole or other PPIs.

• Long-term use may lead to magnesium or vitamin B12 deficiency.

• Monitor for signs of Clostridium difficile-associated diarrhea in prolonged use.

• Use with caution in hepatic impairment.

• Not recommended without clear indication during pregnancy unless prescribed.

Storage:

• Store below 25 °C in a dry place.

• Protect from light and moisture.

• Keep out of reach of children.

Disclaimer:

This medication must be used under the supervision of a licensed healthcare professional. This information is provided for reference only and does not replace professional medical advice. Always follow your physician’s directions.